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mRNA Vaccines Against Bacteria Pathogens

mRNA Vaccines Against Bacteria Pathogens ประเทศไทย

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mRNA Vaccines Against Bacteria Pathogens

In addition to viral antigens, disease-causing bacteria can also cause infections. For example, tuberculosis (TB), infected by Mycobacterium tuberculosis, has long provided the leading cause of death worldwide. However, only few bacterial and parasite antigens have been used in clinical trials for mRNA vaccines, and many of them are still in the preclinical stage.

The use of mRNA vaccines in the future for the prevention of bacterial infections will require further optimization, including the selection of key antigens and antigenic epitopes, periodic injections of different target antigens, and even the direct addition of adjuvanted passive immune compositions.

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non-GMP

Drug Substance, mRNA

0.1~10 mg (mRNA)

Preclinical research such as cell transfection, Analytical method development, Pre-stability studies, Formulation development

Drug Product, LNP-mRNA

GMP, Sterility

Drug Substance, mRNA

10 mg~70 g

Investigational new drug (IND), Clinical trial authorisation (CTA), Clinical trial supply, Biologic license application (BLA), Commercial supply

Drug Product, LNP-mRNA

5000 vials or pre-filled syringes/ cartridges
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