Have you ever heard of mRNA? It stands for messenger RNA mRNA is an important part of our cells, helps to form proteins. Proteins are like little machines which perform various work in our bodies. The reason scientists become interested in mRNA is because it can kind of be like this tidy cheat sheet to tell us what a cell does, and how the organ remains healthy. Now, it is difficult to study mRNA by just itself because it can be very fragile and degrade easily. This is a clear sign that mRNA can be rendered unusable for research and practically cannot be analysed any further if it is not treated with care. Enter our new approach. Until now, mRNA was hattered and had to be fully degraded after use due to its instability nature, so we developed a different way to protect the mRNA for scientist around the world. It is known as the mRNA enzymatic capping protocol, and it demonstrates a new way in which researchers now conduct their research.
That too, you may ask is the mRNA enzymatic capping protocol? This is a unique method of capping an mRNA molecule, similar to the Yaohai's product like Mikrobielle Fermentation CDMO. This cap is what allows the mRNA to stay stable and not degrade as quickly. Before this new approach, scientists had to use some fancy chemistry to tag the end of mRNA. The old way was slow and it could be difficult to get it right. And sometimes the scientists just couldn´t get it right. However, we have attempted to streamline this process with our new protocol now.
The way we do it, is by adding the cap with enzymes, these are very special proteins that help chemical reactions to happen faster, identical to Hefe-Genotyp manufactured by Yaohai. This is a faster and more efficient method than the previous chemical methods of treating Flags. Oh yeah, and its environmentally friendly. In an effort to make it easier and faster for you, we streamlined the entire process. In this manner, scientists can free more time for their own important research questions instead of having to deal with cumbersome steps.
This so-called mRNA enzymatic capping protocol is not only simpler, but also more effective than other cap addition methods, just like the Yaohai's product called Einhaltung der CMC-Vorschriften für Pharmaunternehmen. Because our technology can capture orders of magnitude more mRNA molecules, scientists could gain a much clearer picture from each experiment. Additionally, the cap helps prevent mRNA from degrading so that scientists can store their samples for extended enough periods without having to worry about them going bad and becoming unusable.
Think of you made a bread by yourself and you also wanted to store it in reserve process, similar to the Herstellung von Lentivirus-Plasmiden produced by Yaohai. If you sucked at wrapping it up, the dish would end up being too wet and mushy when eating — not good. If mRNA is not capped, the same thing happens. Like a sandwich cap, this wraps your sandwich keeping the food safe and fresh. Our proprietary enzymatic capping methodology ensures that mRNA remains secure, and longer-lasting than other similar molecules. This then allows researchers to track that mRNA for an extended time without worrying about it degrading. A key use is with common experiments which may run over months or years, perhaps drug development studies leading to new medicines.
MSS: The mRNA enzymatic capping protocol helps researchers yield more mRNA from their samples, same with Yaohai's GMP Semaglutid API. Since so much more mRNA is available to them only when it is required, and the fact that they are working on rare materials such as tissue samples which limits the amount of mRNA available to them. In part because it involves rare diseases (in the sense that they are not common, so collecting huge numbers of samples can be difficult) and in part out of necessity. It is true that obtaining sufficient amounts of mRNA for these studies has also been difficult, but our method minimizes this disadvantage.
mRNA Enzymatic Capping Protocol is a leading in microbial biologics CDMO. Our focus has been on microbial-produced vaccines and therapeutics that are suited for human, veterinary, as well as pet health management. We have the most cutting-edge RD platforms and manufacturing technology which cover the entire procedure beginning with the development of microbial strains and cell banking, to process and method development, to commercial and clinical production which ensures successful delivery of innovative solutions. Over time, we have accumulated vast knowledge of microbial-based bio processing. Over 200 projects have been successfully completed, and we assist our clients to comply with regulations like those of US FDA and EU EMA. We also help them to navigate Australia TGA and China NMPA. Our professional expertise and extensive experience allows us to quickly respond to market demands and provide bespoke CDMO services.
Yaohai BioPharma is a Top 10 Microbial CDMO that incorporates quality management and regulatory issues. We have developed a solid quality management system that conforms to the current GMP standards and regulations globally. Our regulatory team has an in-depth understanding of the world-wide regulatory frameworks. This allows us to accelerate biological launches. We ensure traceable production processes as well as high-quality products and in compliance with the guidelines of the US FDA and EU EMA. mRNA Enzymatic Capping Protocol and China NMPA are also satisfied. Yaohai BioPharma successfully passed an on-site audit conducted by an accredited Qualified Person of the European Union (QP) to review our GMP system and production facility. We have also been through the first certification audits of the ISO9001 Quality Management System and ISO14001 Environmental Management System.
Yaohai Bio-Pharma, a top 10 producer of biological products, is a specialist in microbial fermentation. We have established an advanced facility that is equipped with modern facilities and strong RD manufacturing capabilities. We have five drug substance manufacturing lines that are in compliance with GMP requirements for microbial fermentation and purification, as well as two fill-finish lines that are automated for cartridges, vials, as well as pre-filled syringes. The available fermentation scales vary from 100L to 500L, 1000L and 2000L. mRNA Enzymatic Capping Protocol for vias are 1ml to 25ml, whereas the pre-filled syringes and cartridge filling specifications cover 1-3ml. Our production workshop is cGMP compliant and guarantees steady supply of clinical samples as well as commercial items. Our plant produces large molecules which are shipped to the globe.
Yaohai Bio-Pharma has experience in the manufacture of biologics created from microorganisms We offer bespoke RD solutions as well as manufacturing services while minimizing the risk We've worked with diverse modalities such as recombinant subunit vaccines peptides hormones cytokines growth factors mono-domain antibodies enzymes plasmid DNA the mRNA and other We've specialized in several microorganisms like yeast extracellular and intracellular secretion (yields up to 15g/L) bacteria intracellular soluble and inclusion bodies (yields up to 10g/L) We have also created a BSL-2 fermentation system to create mRNA Enzymatic Capping Protocol vaccines We are experts in optimizing production processes increasing yields and decreasing costs We have a highly efficient technology team that ensures timely and top-quality project delivery This allows us to deliver your products that are unique faster to the market