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Other Proteins

Other Proteins

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Modality

Other Proteins

Microbial expression systems, like bacteria (Escherichia coli) and yeast (Hansenula polymorpha, Pichia pastoris, Saccharomyces cerevisiae) are widely used in the biopharmaceutical industry. Apart from Vaccine, Peptide, Enzyme, Nano-antibody, Antibody fragment, Growth factor, Cytokine, Antigen, and Collagen, the following proteins can also produced in microbial cells.

Types/Family

Protein

Application

Albumin

Human serum albumin (HSA)

As an active substance for low albumin levels or as inactive ingredient

Feline serum albumin (FSA)

Increasing albumin levels and osmotic pressure

Canine serum albumin (CSA)

Bovine serum albumin (BSA)

As a standard reagent in experiments

Chemokine

Stromal cell-derived factor-1 (SDF-1)

Protecting the heart from ischemia-reperfusion injury; stimulating cardiac angiogenesis

Heparin-binding growth factor

Midkine

Exerting activities such as angiogenesis and fibrinolysis.

Osteoblast factor

MEPE fragment

Promoting bone formation and osteoblast proliferation

Apolipoprotein

Clusterin (CLU), Apolipoprotein A

Clearing cellular debris and apoptosis

E3 ubiquitin ligase

Parkin protein

Improving Parkinson's symptoms

Annexin

Annexin 5

Inhibiting inflammation and endothelial activation as a potential therapeutic for sepsis

Neurotoxic peptides

Conopeptides, Conotoxins

For pain management, and cosmetics uses (like anti-wrinkle)

BTX

Fusion protein

Human serum albumin (HSA) fused proteins

Improving pharmacokinetic properties and prolonging the half-life of peptides or proteins (mainly as a half-life extension carrier)

Designed ankyrin repeat proteins (DARPins), like DARPins containing HSA-binding domains

Other fusion proteins

Custom protein

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