|
Generic Name
|
Brand Name/
Alternative Name
|
Expression System
|
Indications
|
Manufacturer
|
R&D Stage
|
|
Filgrastim
|
Neupogen,
|
Escherichia coli (E. coli)
|
Neutropenia
|
Kyowa Kirin Co., Ltd., Amgen, Inc.
|
Approval
|
|
Filgrastim-AAFI, biosimilar
|
Nivestym, Nivestim
|
E. coli
|
Neutropenia
|
Hospira, Inc., Pfizer Europe MA EEIG
|
Approval
|
|
Filgrastim-SNDZ, biosimilar
|
ZARXIO
|
E. coli
|
Neutropenia
|
Sandoz, Inc., Clariant AG, Sandoz GmbH
|
Approval
|
|
TBO-Filgrastim
|
GRANIX
|
E. coli
|
Neutropenia
|
Sicor Biotech UAB, Teva Pharmaceutical.
|
Approval
|
|
Filgrastim biosimilar
|
RELEUKO, FILGRASTIM-AYOW
|
E. coli
|
Neutropenia, Granulocytopenic Fever
|
Kashiv Biosciences LLC
|
Approval
|
|
Filgrastim biosimilar
|
瑞白
|
E. coli
|
Neutropenia
|
Qilu pharmaceutical
|
Approval
|
|
Filgrastim biosimilar
|
金磊赛强, Scimax, Filgrastim-aafi, Filgrastim-sndz, G-CSF, Tbo-filgrastim
|
E. coli
|
Neutropenia
|
GenSci
|
Approval
|
|
Filgrastim biosimilar
|
泉升
|
E. coli
|
Neutropenia
|
Quangang Pharma
|
Approval
|
|
Filgrastim biosimilar
|
保力津
|
E. coli
|
Neutropenia
|
Chengdu Institute of Biological Products
|
Approval
|
|
Recombinant human G-CSF
|
白特喜
|
E. coli
|
Neutropenia
|
SINOVAC Biotech
|
Approval
|
|
Filgrastim biosimilar
|
TX-01
|
Pending update
|
Neutropenia
|
Tanvex Biopharma, Inc
|
Approval
|
|
Filgrastim
|
Accofil
|
Pending update
|
Neutropenia
|
Accord Healthcare SLU
|
Approval
|
|
Filgrastim
|
Grastofil
|
Pending update
|
Neutropenia
|
Accord Healthcare SLU
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Fresenius Kabi AG
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Biolotus Biotech Ltda.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Center For Molecular Immunology
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Rubin Ltd
|
Approval
|
|
Filgrastim biosimilar
|
Ficocyte
|
Pending update
|
Neutropenia
|
Nanogen Pharmaceutical Biotechnology JSC
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Zydus Cadila Healthcare Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Emcure Pharmaceuticals Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Fuji Pharma Co., Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Blau Pharmaceuticals
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Acute myeloid leukemia, Lymphoma, Myelodysplastic syndrome, Neutropenia
|
Pooyesh Darou Biopharmaceuticals Co.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
tumor
|
Chandra Bhagat Pharma Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Neiss Labs Limited
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
PT Kalbe Farma Tbk
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
RPG Life Sciences Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Zuventus Healthcare Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Claris Lifesciences Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Fiprima
|
Pending update
|
Neutropenia
|
Eurofarma
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
granulocytopenic fever
|
Harvest Moon BV
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
International Centre for Genetic Engineering and Biotechnology (ICGEB)
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
AqVida GmbH
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Biocon Biopharmaceuticals Pvt Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Cjsc Generium
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Pharmapark LLC
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Reliance Life Sciences Pvt Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Laboratorios AC Farma SA
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Laboratorios Chalver de Colombia SA
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
RAS Lifesciences Pvt Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Probiomed SA de CV
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Tumor, Neutropenia
|
Zenotech Laboratories Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Dr. Reddy's Laboratories Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia, Breast Cancer
|
Dong-A ST Co., Ltd., Dong-A Pharmaceutical Co., Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
North china pharmaceutical
|
Approval
|
|
Filgrastim biosimilar
|
特尔津, Teerjin, FILTIM, rHuG-CSF, Topneuter
|
Pending update
|
Neutropenia
|
Ranbaxy Laboratories, Amoytop
|
Approval
|
|
Filgrastim biosimilar
|
吉粒芬, Jilifen
|
Pending update
|
Neutropenia
|
Huadong Medicine
|
Approval
|
|
Filgrastim biosimilar
|
立生素, Li Sheng Su
|
Pending update
|
Neutropenia
|
Beijing Shuanglu
|
Approval
|
|
Filgrastim biosimilar
|
Mielastra
|
Pending update
|
Neutropenia
|
Abbott Laboratories
|
Approval
|
|
Filgrastim biosimilar
|
Leuco-Plus 300, Leuco-Plus-300, SBS-6002
|
Pending update
|
Neutropenia
|
Apexcela Co., Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Biofigran, Colstim, Granulostim, Neutromax
|
Pending update
|
Neutropenia
|
Biosidus SA
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
CJ CheilJedang Corp.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Elea Spa
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Incepta Pharmaceuticals Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Neutrofil
|
Pending update
|
Neutropenia
|
Laboratorio Varifarma SA
|
Approval
|
|
Filgrastim biosimilar
|
Biofilgran
|
Pending update
|
Neutropenia
|
Landsteiner Scientific SA de CV
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Sedico BV
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Siam Bioscience Co. Ltd.
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Sudershan Biotech Ltd
|
Approval
|
|
Filgrastim biosimilar
|
Neocyte
|
Pending update
|
Neutropenia
|
unilab AG
|
Approval
|
|
Recombinant human granulocyte stimulating factor
|
津恤力
|
E. coli
|
Neutropenia
|
CSPC Baike (Yantai) Biopharmaceutical Co. Ltd.
|
Approval
|
|
Recombinant human G-CSF
|
rial, riyakin
|
Pending update
|
Neutropenia
|
Hapharm
|
Approval
|
|
Recombinant human G-CSF
|
Jie Xin
|
Pending update
|
Neutropenia
|
Jiangsu Wuzhong
|
Approval
|
|
Recombinant human G-CSF
|
Ruixuexin
|
Pending update
|
Neutropenia
|
Weiming Xinpengbio
|
Approval
|
|
Recombinant human G-CSF
|
欣粒生
|
E. coli
|
Neutropenia
|
Sihuan shengwu
|
Approval
|
|
Filgrastim biosimilar
|
Grasalva
|
Pending update
|
Neutropenia
|
Teva Pharmaceutical Industries Ltd.
|
Approval
|
|
Recombinant human G-CSF
|
赛格力, SunGran
|
Pending update
|
Neutropenia
|
Sunwaybio
|
Approval
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Lunan
|
Submit for approval
|
|
Filgrastim biosimilar
|
Filgrastim biosimilar, GranNEX
|
Pending update
|
Neutropenia
|
MYCENAX
|
Submit for approval
|
|
Filgrastim biosimilar
|
BK 0023, BK-0023, Filgrastim biosimilar
|
Pending update
|
Neutropenia
|
Bio-Ker s.r.l.
|
phase III
|
|
Filgrastim biosimilar
|
Filgrastim biosimilar, Neutrogen
|
Pending update
|
Neutropenia
|
Virchow Group
|
phase III
|
|
Filgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Bio Genomics, Inc.
|
phase I
|
|
Filgrastim biosimilar
|
MNGX-100, Filgrastim
|
Pending update
|
Neutropenia
|
MenoGenix, Inc.
|
phase I
|
|
MW-05
|
MW 05
|
Pending update
|
Neutropenia
|
Mabwell
|
phase III
|
|
Pegfilgrastim
|
Neulasta, Neupopeg, G-Lasta
|
E. coli
|
Stem cell mobilization, Reduction of neutral granulocytes, reduction of granulocytes and heating, Infection
|
Kyowa Kirin, Amgen, Inc.
|
Approval
|
|
Pegfilgrastim biosimilar
|
STIMUFEND, PEGFILGRASTIM-FPGK
|
Pending update
|
Granulocytopenic fever, Infection, Tumor
|
Fresenius Kabi USA LLC, Fresenius Kabi Deutschland GmbH, Merck Serono SA
|
Approval
|
|
Pegfilgrastim-PBBK biosimilar
|
FYLNETRA, PEGFILGRASTIM-PBBK
|
Pending update
|
Neutropenia
|
Kashiv Biosciences LLC
|
Approval
|
|
Pegfilgrastim-APGF
|
Nyvepria
|
Pending update
|
Neutropenia, Neutropenic fever, Infection
|
Pfizer Europe MA EEIG, Hospira, Inc.
|
Approval
|
|
Pegfilgrastim
|
Grasustek
|
Pending update
|
Neutropenia
|
\"JUTA\" Pharma GmbH
|
Approval
|
|
Pegfilgrastim-Bmez
|
ZIEXTENZO
|
Pending update
|
Neutropenic fever, infection, neutropenia
|
Sandoz GmbH, Clariant AG, Sandoz, Inc.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Cegfila
|
Pending update
|
Neutropenia
|
Mundipharma
|
Approval
|
|
Pegfilgrastim
|
Pelgraz
|
Pending update
|
Neutropenia
|
Accord Healthcare SLU
|
Approval
|
|
Pegfilgrastim-CBQV
|
UDENYCA
|
Pending update
|
Hematopoietic subsyndrome of acute radiation syndrome, Granulocytopenic fever, Infection
|
Coherus BioSciences, Inc.
|
Approval
|
|
Pegfilgrastim-Jmdb
|
Fulphila
|
Pending update
|
Neutropenia, Neutropenic fever, Infection
|
Mylan Pharmaceuticals, Inc., MyLan SAS
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Rubin Ltd
|
Approval
|
|
Pegfilgrastim biosimilar
|
新瑞白
|
Pending update
|
Neutropenia
|
Qilu pharmaceutical
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Dong-A Pharmaceutical Co., Ltd.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Zydus Cadila Healthcare Ltd.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Harvest Moon BV
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Dr. Reddy's Laboratories Ltd.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Apotex, Inc.
|
Approval
|
|
Pegylated recombinant human G-CSF
|
津优力
|
Pending update
|
Neutropenia
|
CSPC Baike (Yantai) Biopharmaceutical Co. Ltd.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Beijing Shuanglu
|
Submit for approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
AMEGA Biotech
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pegfilgrastim biosimilar, Tinapeg
|
Pending update
|
Neutropenia
|
ATG ( Arya TinaGene) Biopharmaceutical
|
Approval
|
|
Pegfilgrastim biosimilar
|
PegaGen, Pegylated filgrastim
|
Pending update
|
Neutropenia
|
Cinnagen
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Emcure Pharmaceuticals Ltd.
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Nanogen Pharmaceutical Biotechnology JSC
|
Approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Union Square Ventures LLC
|
Submit for approval
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Lunan
|
phase III
|
|
Pegfilgrastim biosimilar
|
R-TPR-029, Pegfilgrastim biosimilar
|
Pending update
|
Neutropenia
|
Reliance Life Sciences Pvt Ltd.
|
phase III
|
|
Pegfilgrastim ANF
|
ANF-Rho, PEG G CSF ANF
|
Pending update
|
Neutropenia
|
Prolong Pharmaceuticals LLC
|
phase II
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
MegaLabs ZAO
|
phase I
|
|
Pegfilgrastim biosimilar
|
G-CSF/PEG 20K
|
Pending update
|
Neutropenia
|
Bio-Ker s.r.l.
|
phase I
|
|
Pegfilgrastim biosimilar
|
PEG30-rhG-CSF
|
Pending update
|
Neutropenia
|
PegBio
|
phase I
|
|
Pegfilgrastim biosimilar
|
Pending update
|
Pending update
|
Neutropenia
|
Ask pharm
|
phase I
|
|
Pegylated human G-CSF
|
PEG-rhG-CSF, 升白针
|
Pending update
|
Neutropenia
|
Kexing Bio-Pharma
|
phase I
|
|
Pegylated recombinant human G-CSF
|
Pending update
|
Pending update
|
Neutropenia
|
Ask pharm
|
phase I
|
|
Pegylated recombinant human G-CSF
|
Pending update
|
Pending update
|
Neutropenia
|
Huadong Medicine
|
phase III
|
|
PEGylated Human G-CSF
|
申力达
|
E. coli
|
Neutropenia
|
Lunan
|
Approval
|
|
QL-0605
|
PEG-rhG-CSF
|
Pending update
|
Neutropenia
|
Qilu pharmaceutical
|
phase I
|
|
Pegteograstim
|
Neurapeg
|
E. coli
|
Neutropenia
|
GC Biopharma (formerly Green Cross Corporation)
|
Approval
|
|
Empegfilgrastim
|
Pending update
|
Pending update
|
Neutropenia
|
Biocad CJSC, Biocad Medical.
|
Approval
|
|
Eflapegrastim
|
Eflapegrastim-xnst, 罗夫登, Rolvedon, Rolontis, LAPS-GCSF analog
|
E. coli
|
Messor cells reduced sexual heating, Infection, Nymnomic granulocyte reduction, Breast cancer, lymphoma, physical tumor
|
Spectrum Pharmaceuticals, Hanmi Pharmaceutical.
|
Approval
|
|
Lipegfilgrastim
|
Lonquex
|
E. coli
|
Neutropenia
|
Teva Pharmaceutical Industries Ltd.
|
Approval
|
|
Nartograstim
|
genetical recombination
|
E. coli
|
Leukocyte reduction, neutral granulocyte decrease
|
Kyowa Hakko Kirin Pharma, Yakult Honsha.
|
Approval
|
|
Lenograstim (Genetical Recombination)
|
Granocyte
|
Pending update
|
Acute myelin leukemia, head and neck tumor, urinary tract cancer, acute lymphocyte leukemia, decrease in neutrophils
|
Chugai Pharmaceutical Co., Ltd.
|
Approval
|
|
Benegrastim
|
Ryzneuta, F-627, CSF-Fc fusion protein
|
CHO cell
|
Neutropenia, Fever, Breast cancer, Neutropenic fever, Parkinson's disease
|
Evive Health LLC, Evive Biotech
|
Approval
|
|
Lenograstim biosimilar
|
Lenobio, Lenograstim Biosidus, Leumostin
|
Pending update
|
Neutropenia
|
Biosidus SA
|
Approval
|
|
Albumin- G-CSF fusion protein
|
8MW0511
|
yeast
|
Leukopenia
|
Mabwell
|
phase III
|
|
Albumin- G-CSF fusion protein
|
Pending update
|
yeast
|
Heatic neutral granulocyte reduction caused by chemotherapy
|
Foremost Group
|
phase II
|
|
BBT-015
|
PEGylated G-CSF
|
Pending update
|
Acute radiation syndrome, decrease in neutral granulocytes
|
Bolder BioTechnology, Inc.
|
phase I
|
|
Mecapegfilgrastim
|
艾多
|
Pending update
|
Neutropenia
|
Jiangsu Hengrui Pharmaceuticals
|
Approval
|
|
Y-branched pegylated human G-CSF
|
Pegfilgrastim, YPEG-filgrastim, YPEG-G-CSF, YPEG-rhG-CSF
|
Pending update
|
Neutropenia
|
Amoytop
|
Submit for approval
|
EN
AR
HR
CS
DA
NL
FI
FR
DE
EL
IT
JA
KO
NO
PL
PT
RO
RU
ES
SV
IW
ID
LV
LT
SR
SK
SL
UK
VI
ET
HU
TH
TR
FA
AF
MS
BE
MK
UR
BN
