Circ-RNA, have you heard of it before? Circular RNA (Quite literally — it means circular…RNA. CircRNA is being researched by scientists to know whether it can indicate diseases inside our body. A biomarker is a molecule in your body (like proteins or DNA) which can be used to tell whether you are sick and have a particular disease. Like a signal, or clue doctors can use to figure out what is going on inside of us. In next few posts, Yaohai will post the technology of (quantitative) circRNA testing with all followers.
Scientists can identify circRNA in our blood, but they need special methods, which are like tools or techniques that help them in their research. First of all they do is take small sample of our blood, that very little and then with the use of machines circRNA is travelled across. They also do RT-PCR called reverse transcription polymerase chain reaction. This technique assists the scientists to amplify the circRNA, so that they can quantify it easily in our blood. This is how the Yaohai technique works to help doctors an scientists make all diagnoses quickly, which is very important since finding all diseases at an early stage does lead to sub optimal treatment.
The relationship between circRNA and diseases are still being figured out by scientist, but they have already discovered some very fascinating stuff! For instance, some circRNA species are more abundant in certain cancers. That is how this paper makes the case that circRNA could be used to detect cancer long before it manifests as any symptoms, such as pain or simply feeling unwell. Other circRNA have been associated with diseases such as Alzheimer's and Parkinson's. They are illnesses that have a big impact on everything from the way people interpret reality to being able to move their limbs It also means that we could have an important testing capacity for circRNA, which would give us better insights and treatment options for these conditions which will make a difference in some people lives.
Personalized medicine is an alternative way to provide the most appropriate treatments for patients based on a genetic barcode — something more like code from which life is built. The new study provides a comprehensive analysis for the expression profiling in several common circRNAs, its potential diagnostic values and particularly guides physician to diagnose sick individuals without symptoms which is relevant in precision medicine. This results in quicker initiation of treatment leading to symptomatic relief at an earlier time boosting overall heath status. This way doctors can help their patients better by recognizing the diseases at an earlier stage. CircRNA tests can also be used to identify effective treatments based on an individuals unique genes, so that each patient receives care tailored just for them.
The method of Yaohai to test circRNA is not a burden on human beings, allowing us to exam the existence of diseases before they are apparent and we can treat them so early. They have even developed a test that could detect circRNA in a single drop of blood! That means patients wont have to undergo large procedures just to get blood tests, which are invasive. They also incorporate high-tech methods of examining the circRNA, which in turn increases the precision of the tests. That means doctors can rely on these tests to make thoughtful decisions about treatment for their patients. Yaohai's circRNA testing gives doctors and patients the assurance that nothing which can be done to help patients is left undone.
circRNA Circulation Efficiency Testing is a leading in microbial biologics CDMO. Our focus has been on microbial-produced vaccines and therapeutics that are suited for human, veterinary, as well as pet health management. We have the most cutting-edge RD platforms and manufacturing technology which cover the entire procedure beginning with the development of microbial strains and cell banking, to process and method development, to commercial and clinical production which ensures successful delivery of innovative solutions. Over time, we have accumulated vast knowledge of microbial-based bio processing. Over 200 projects have been successfully completed, and we assist our clients to comply with regulations like those of US FDA and EU EMA. We also help them to navigate Australia TGA and China NMPA. Our professional expertise and extensive experience allows us to quickly respond to market demands and provide bespoke CDMO services.
Yaohai Bio-Pharma is experienced in biologicals derived from microbial sources. We provide customized RD solutions and manufacturing, while minimising potential risks. We have worked on various modalities, including recombinant subunit vaccines, peptides hormones, cytokines growth factors, single-domain antibodies enzymes, plasmid DNA various mRNAs, and more. We have specialized in multiple microorganisms, including circRNA Circulation Efficiency Testing intracellular and extracellular secretion (yields up to 15g/L) and intracellular soluble bacteria and inclusion body (yields up to 10g/L). We have also established a BSL-2 fermentation platform to create bacteria-based vaccines. We are experts in improving processes, boosting product yields, and decreasing production costs. We have a highly efficient technology team that ensures timely and top-quality project delivery. This allows us to bring your unique products faster to market.
Yaohai Bio-Pharma, a circRNA Circulation Efficiency Testing manufacturer of biological products, is a specialist in microbial fermentations. We have built a modern factory equipped with modern facilities and strong RD and manufacturing capabilities. Five drug substance production lines that are compliant with GMP standards for microbial purification and ferment, as well as two fill and finish lines for vials as well as cartridges, as well as needles that are pre-filled, are readily available. The available fermentation scales vary from 100L to 500L, 1000L, to 2000L. Filling volumes vary from 1ml to 25ml. Syringes or cartridges pre-filled are filled with the equivalent of 1-3ml. Our cGMP-compliant production facility ensures the availability of stable clinical samples and commercial products. The big molecules that are produced at our plant are readily available for international delivery.
Yaohai BioPharma, a top 10 circRNA Circulation Efficiency Testing, combines regulatory affairs and quality control. We have a quality system that is compliant with current GMP standards and regulations around the globe. Our regulatory team has deep understanding of world-wide regulatory frameworks. This lets us accelerate biological launches. We ensure traceable production procedures with high-quality products as well as compliance with the regulations of the US FDA and EU EMA. Australia TGA and China NMPA is also fulfilled. Yaohai BioPharma successfully passed an in-person audit conducted by an accredited Qualified Person of the European Union (QP) to examine our GMP system and production facility. We have also passed the initial certification audits of the ISO9001 Quality Management System and ISO14001 Environmental Management System.