At Yaohai, we’re particularly good at producing something called VHH trimer antibodies. These special antibodies are important because they treat many different diseases found in people. VHH trimer antibodies consist of three small domains. These sections are known as VHH domains, and they bond to the body’s specific targets in this configuration. This is how they help combat disease and keep humans healthy.
Previously it was a laborious process to generate VHH trimer antibodies. It was hard and very costly. So people who had elaborate machines and knew how to work them did all the work. At Yaohai, however, we have discovered faster, easier, lower-cost ways of making these antibodies. This represents a major jump forward, not just for us, but for the patients who need these therapies.
We also developed clever and sophisticated so we can clean up and prepare the antibodies after they are made. This allows us to extract the antibodies from the cell culture and prepare them for use in actual medical treatments. These novel ways of working also help save costs, which means that we can produce the VHH trimer antibodies for a fraction of the cost we used to pay. Sounds like great news for everyone involved!
While we have been discovering ways to produce these antibodies more effectively, we have also been looking for means to increase their availability further to meet the growing demand in medicine. And VHH trimer antibodies can play a significant role in this context, as many doctors and researchers are in search of effective treatments. We are collaborating with leading pharmaceutical companies and research groups to develop new therapies based on VHH trimer antibodies.
While at Yaohai, we assembled a group of specialists with considerable knowledge and know-how in VHH trimer antibodies. As such, these team members provide a wealth of experience to our practice, making us very formidable in what we do. We employ state of the art technologies and approaches, in order to enhance our antibody production capabilities. This is critical to ensuring our antibodies are of the highest quality and purity.
We are continuously looking to further refine and improve VHH trimer antibody development. We want to be a leading force in the field of genome editing … and be at the forefront of developing new and innovative treatments for patients that really need those therapies. We seek to extend the frontiers of what is possible in this vital area of research.
We are focused on constantly improving our workflow as we strive to continue being a leader in the generation of VHH trimers, and thus, continuously seek out and implement novel solutions. Such as new software packages and real-time data tools that feed into our advanced machines that we have continuously invested in as an organization. This allows us to iterate and build on each step sooner than later.
Yaohai Bio-Pharma is experienced in biologicals derived from microbial sources. We provide customized RD solutions and manufacturing, while minimising potential risks. We have worked on various modalities, including recombinant subunit vaccines, peptides hormones, cytokines growth factors, single-domain antibodies enzymes, plasmid DNA various mRNAs, and more. We have specialized in multiple microorganisms, including VHH Trimer Manufacturing intracellular and extracellular secretion (yields up to 15g/L) and intracellular soluble bacteria and inclusion body (yields up to 10g/L). We have also established a BSL-2 fermentation platform to create bacteria-based vaccines. We are experts in improving processes, boosting product yields, and decreasing production costs. We have a highly efficient technology team that ensures timely and top-quality project delivery. This allows us to bring your unique products faster to market.
Yaohai Bio-Pharma, a leader in VHH Trimer Manufacturing of microbial biologics, is located in Jiangsu. We are focusing on microbially produced therapeutics and vaccines that are suited for human, veterinary, and pet health management. We have modern RD as well as manufacturing technology platforms that cover the entire process, from engineering microbial strains, cell banking, process and method development, through to commercial and clinical manufacturing, making sure that we can ensure the successful supply of the most cutting-edge solutions. We have acquired a large amount of experience in the microbial bio processing field. More than 200 projects have been completed successfully and we support our clients in overcome regulations such as those of the US FDA and EU EMA. We also aid them with Australia TGA and China NMPA. We are able to respond rapidly to market requirements and offer customized CDMO services thanks to our experience and expertise.
Yaohai Bio-Pharma, a top 10 manufacturer of biological products, specializes in microbial fermentation. We have created a VHH Trimer Manufacturing manufacturing facility with robust RD capabilities and cutting-edge manufacturing facilities. Five drug substance production lines conforming to GMP standards to purify and ferment microbial cells, as well as two fill and finish lines for vials and cartridges, as well as needles that are pre-filled, are available. The available fermentation scales include 100L, 500L, 1000L and 2000L. Specifications for filling vials range from 1ml - 25ml. the pre-filled cartridge or syringe filling specifications range from between 1-3ml. The production workshop is cGMP-compliant and provides a stable supply of commercial products and clinical samples. Our facility produces large molecules that are shipped worldwide.
Yaohai BioPharma, a top 10 Microbial CDMO that integrates quality management and regulatory affairs. Our quality system that is compliant with current GMP standards as well as international regulations. Our team of regulatory experts is proficient in global regulatory frameworks to accelerate biological launches. We ensure traceable production procedures quality products, as well as conformity with the requirements of the VHH Trimer Manufacturing and EU EMA. Australia TGA and China NMPA are also met. Yaohai BioPharma successfully passed an in-person audit conducted by a Qualified Person of the European Union (QP) to examine our GMP system and production facility. We also completed the initial certification audits of the ISO9001 Quality Management System and ISO14001 Environmental Management System.