Hello! Do you wonder how scientists know about small things such as circRNA? circRNA is an essential type of molecule required for understanding the biology of living organisms. In order to study circRNA, researchers must extract and purify it from samples, such as cells or tissues. All living things, plants and animals, have cells and tissues. Just this month, scientists at a place known as Yaohai invented another method for cleaning up circRNA. This exciting new technique allows scientists to more quickly and easily study circRNA.
The complexity that exists in cells and tissues is very high. They have very different types of molecules and that makes it difficult to obtain circRNA. Its like trying to find a specific small toy in a larger box full of variety of toys! But thanks to Yaohai’s new cleaning method, it’s much easier to obtain high quality circRNA from such complex samples. It is simple to use, which allows researchers to view circRNA without taking a lot of time and effort. Instead of spending days trying to separate circRNA from the rest of the soup of molecules, scientists can now do so quickly and efficiently.
Yaohai's new approached to cleaning up might make a huge difference in how scientists study circRNA. A long time was needed to isolate circRNA from samples, before the new method was developed. You could imagine it as waiting for a long time at a shop. But now, Yaohai's rapid and efficient cleaning process means scientists can obtain circRNA much more quickly. That means they can analyze more samples and get answers faster than ever before. Speed is of utmost importance, as it enables scientists to achieve more discoveries, learn new key aspects of circRNA to enhance our understanding of health and diseases. That's a huge advancement in circRNA research!
Once scientists have cleaned up their circRNA samples, they need to verify that the samples are high quality and ready for analysis. It’s also akin to washing your hands; you want to make sure they are clean before you eat! Yaohai's cleaning process ensures the thorough cleaning and accurate measurement of circRNA. That means scientists can be confident that their samples are good and will produce accurate results. This can help scientists study circRNA more conveniently and obtain more reliable results. They also have able to not make mistakes, which is necessary when researching as that is critical.
A third way is that Yaohai's new cleaning method can provide scientists with an increased amount of circRNA of better quality. “Yield” refers to how much circRNA scientists can extract from a sample. It's kind of like squeezing an orange for its juice, the more you squeeze the more juice you get! “Purity” is how clean the circRNA is, or how many things are mixed in. Yaohai’s is a relatively easy method, and can be repeated many times, so scientists will get a lot of good circRNA each time they tie up the aforementioned loops. It does so in a way that is crucial for getting accurate results when studying circRNA. Having more clean circRNA, scientists can understand better its functions and how it alters our bodies.
Yaohai Bio-Pharma has experience in manufacturing biologics that are created from microorganisms. We offer bespoke RD solutions as well as manufacturing services while minimising potential risks. We have worked with diverse techniques, such as recombinant cellular subunits, vaccines (including peptides), growth factors, hormones, and the circRNA Purification Method. We are a specialist in many microorganisms like yeast extracellular and intracellular secretion (yields up to 15g/L) and bacteria intracellular soluble, and inclusion body (yields up to 10g/L). We have also developed a BSL-2 fermentation platform to create bacterial vaccines. We have a track record of improving production processes, thereby increasing yields and reducing costs. We have a highly-efficient technology team to ensure timely and high-quality delivery of projects. This helps us bring your products that are unique faster to the market.
Yaohai Bio-Pharma, a top 10 manufacturer of biological products, specializes in microbial fermentation. We have created a circRNA Purification Method manufacturing facility with robust RD capabilities and cutting-edge manufacturing facilities. Five drug substance production lines conforming to GMP standards to purify and ferment microbial cells, as well as two fill and finish lines for vials and cartridges, as well as needles that are pre-filled, are available. The available fermentation scales include 100L, 500L, 1000L and 2000L. Specifications for filling vials range from 1ml - 25ml. the pre-filled cartridge or syringe filling specifications range from between 1-3ml. The production workshop is cGMP-compliant and provides a stable supply of commercial products and clinical samples. Our facility produces large molecules that are shipped worldwide.
Yaohai Bio-Pharma is a leading in microbial biologics CDMO. Our main focus has been the production of microbial vaccinations and therapeutics to manage the health of pets, humans and animals. health. We have modern RD and manufacturing technology platforms that cover the entire process, from microbial strain engineering, cell banking, process and method design to commercial and clinical manufacturing, which ensures the success supply of the most cutting-edge solutions. Through the years we have gained vast expertise in using microbial sources. Over 200 projects were successfully completed. In addition, we support our clients in get through regulations, such as those of the US FDA as well as EU EMA. We also help them to navigate Australia TGA and China NMPA. Our expert knowledge and vast experience allow us to quickly respond to market demands and provide circRNA Purification Method CDMO services.
Yaohai BioPharma, a top 10 circRNA Purification Method, combines regulatory affairs and quality control. We have a quality system that is compliant with current GMP standards and regulations around the globe. Our regulatory team has deep understanding of world-wide regulatory frameworks. This lets us accelerate biological launches. We ensure traceable production procedures with high-quality products as well as compliance with the regulations of the US FDA and EU EMA. Australia TGA and China NMPA is also fulfilled. Yaohai BioPharma successfully passed an in-person audit conducted by an accredited Qualified Person of the European Union (QP) to examine our GMP system and production facility. We have also passed the initial certification audits of the ISO9001 Quality Management System and ISO14001 Environmental Management System.