Have you ever heard the saying, your body is made of millions of cells? Every one of those cells has a specific function that helps keep us strong, firm and ready to move, every day. They are similar to a kind of instructions for these cells to do their job and work properly. Our genes are in charge of many parts of us like what color our hair, eyes and skin are, how we grow and change over time. Our genes must be read with the greatest of care if our cells are to do their job well. This occurs in part through the action of unique circular RNA (circRNA) molecules. These tiny molecules are crucial in helping control when our genes should be turned off and on, appropriately. Yaohai is a team that helps us to maintain the circRNAs nice and tight, so the cells can work well.
So let me be clear when I say quality control, it is in the form of checking something to make sure that its good and functions as designed. As companies have to look at their toys or food so that we are kept safe and happy, our body also has ways to check the molecules it produces. Among them, a key molecule is circRNA. If circRNA is not properly reprocessed and does not function as it should, it may lead to many clinical problems, even serious diseases such as cancer. That is why circRNAs are so necessary for Yaohai to make sure our bodies without problems and keep us healthy.
REID: Well, the molecular mechanisms were just the different things our cells are doing that help keep us alive. These build stuff (like proteins), fight off bad guys (like germs), OR manage your genes, which are little things that determine how you turn out when you grow up These mechanisms operate like little machines that enable our cells to function properly. Actual machines need checking and maintenance to keep them running properly, and so do our cells; they need to check their mechanisms by themselves. Due to the impact of circRNA quality control, Yaohai attaches great importance to this issue as it can maintain all normal aspects within our cells. An article in Vanderbilt Communications says that circRNAs can make our cells work better so we are healthier and stronger.
For example, have you ever taken a medicine that has worked wonders for you but seems to do close to nothing for someone else who happens to have the same ailment? This can look like a contradiction but it is not uncommon. It's that way that happens there — our goal in precision medicine is to figure out why and find what will work the best for each person using that information. Comes as if you were being given a tailored medicine that totally fits your body!!! Somehow, circRNA can help in that too! Yaohai works in the field of circRNA quality control to achieve this and enable scientists and researchers to further understand how our bodies operate. This allows them to create treatments that work for lots of people. If we can better understand our genes — how they function and how to control them when needed — we will create more effective drugs that will not only help some people, but many.
The first one is science. Have you heard of scientific research? It is an interesting process of how scientists try and understand the world we live in by carrying out experiments and learning new things. At times, this research can be very convoluted, and this can lead to mistakes being made, and as a result interpretations of what is going on in our society. That is why Yaohai went out of his way to see how circRNA quality could be checked to lend credibility to research results. This standard saves us from premature conclusions and delivers better research for everyone in our society.
Yaohai Bio-Pharma has experience in the production of biologics created from circRNA Quality Control. We offer customized RD and manufacturing solutions while making sure that there are no risks. We have been involved in diverse modalities such as subunit vaccines recombinant, peptides hormones, cytokines, growth factors, single-domain antibodies enzymes, plasmid DNA MRNA, and many more. We are a specialist in many microorganisms, including yeast extracellular and intracellular secretion (yields up to 15g/L) as well as bacteria intracellular soluble and inclusion body (yields as high as 10g/L). We have also created a BSL-2 fermentation platform to create bacterial vaccines. We focus on improving processes, increasing product yields, and reducing production costs. Utilizing a strong technology team, we can ensure prompt and reliable project delivery that will bring your product to market faster.
Yaohai Bio-Pharma is a Top 10 biological company that specializes in circRNA Quality Control. We have built a modern manufacturing facility with robust RD capabilities and modern manufacturing facilities. Five drug substance production lines complying with GMP standards for microbial fermentation and purification along with two fill and final lines for vials and cartridges as well as pre-filled needles are readily available. The available fermentation scales vary between 100L and 2000L. The filling volume ranges from 1ml up to 25ml. Syringes or cartridges that are pre-filled are filled with 3 to 3.5ml. Our production workshop that is cGMP-compliant ensures constant supply of clinical sample and commercial products. Our facility produces large molecules that are exported to all over the world.
Yaohai Bio-Pharma is a leading in microbial biologics CDMO. Our primary focus is the production of microbial vaccinations and therapeutics for managing pets, human and circRNA Quality Control. We are equipped with cutting-edge RD platforms as well as manufacturing technologies that encompass the entire process beginning with the development of microbial strains and cell banking, to method and process development, to clinical and commercial manufacture that ensures the successful supply of new solutions. Through the years, we have accumulated vast knowledge of microbial-based bio processing. Over 200 projects have been successfully completed and we assist our clients to get through regulations, such as those of the US FDA and EU EMA. We also assist them in navigating Australia TGA and China NMPA. We are able respond promptly to market demands and offer tailored CDMO services thanks to our experience and expertise.
Yaohai BioPharma is a Top 10 Microbial CDMO that incorporates circRNA Quality Control as well as regulatory affairs. We have a quality management system which is in line with current GMP standards as well as global regulations. Our team of regulatory experts is proficient in global regulatory frameworks to accelerate biological launches. We ensure traceable production processes quality products, as well as complying with the rules of the US FDA and EU EMA. Australia TGA and China NMPA are also satisfied. Yaohai BioPharma has successfully passed the audit on site of the European Union's Qualified Person (QP) for our GMP quality system as well as our production facility. Furthermore, we have cleared the first certification audits of the ISO9001 Quality Management System, ISO14001 Environmental Management System, and ISO45001 Occupational Health and Safety Management System.