IL-2 mRNA expresses human Interleukin-2 (IL-2) protein, originally called T-cell growth factor (TCGF). Interleukin-2 (IL-2) is a multifunctional cytokine which can stimulate the differentiation and proliferation of T lymphocytes and other cell types including B lymphocytes, natural killer (NK) cells, lymphokine-activated killer (LAK), and monocytes/macrophages. Interleukin 4 (IL-4) and Interleukin 7 (IL-7) share a gamma chain with the heterotrimeric protein complex that is the IL-2 receptor (IL-2R), via which IL-2 transmits its signals.
Yaohai Bio-Pharma offers unmodified or N1Ψ modified IL-2 mRNA, with Cap1 structure, optimized codons, engineered UTR and 110nt polyA tail, to improve mRNA stability and translation efficiency.
Product
IL-2 mRNA, Cap1, poly(A) tail, unmodified or modified mRNA
| Product |
IL-2 mRNA |
| Cat. No |
mP007 |
| RNA Content |
100 µg~10 mg (OD260) |
| Purity |
A260/A280 |
| Identify and Purity |
Agarose Gel Electrophoresis (AGE) |
| 5’Cap |
Cap1 |
| 3’ poly(A) tail |
110±5 nt |
| Base Modification |
Unmodified, N1Ψ |
| Buffer |
RNase free water (liquid) |
| Shipping |
Ship with dry ice; or under ambient temperature |
| Storage |
● Liquid, at or below -20°C
● Lyophilized powder, at 4°C
|
| Application |
Gene replacement
|
Other Customizable Options
| 5' Cap |
● Uncapped
● Cap0, co-capped
● Cap1, co-capped
● Cap1, enzymatic capping
|
| 5’ UTR/3’ UTR |
● Nature UTR sequence
● Mutant/Engineered UTR sequence
|
| 3' PolyA Tail |
● 100A ~120A Tail (recommended)
● Segmented polyA tail
● Other custom tail
|
| Modified nucleosides |
● Unmodified bases,
● Pseudouridine (Ψ),
● N1-Methylpseudouridine (N1Ψ),
● 5-methylcytosine (m5C),
● 5-methyluridine (m5U),
● 5-methoxyuridine (5moU),
● 2-thiouridine (s2U),
● 2′-O-methyl-U
● Others
|
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