IL-12 mRNA expresses human Interleukin-12 (IL-12) protein, also referred to as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF). Interleukin-12 (IL-12) is a heterodimeric cytokine that plays an essential role in the immune system's response to infections and cancer.
Yaohai Bio-Pharma offers unmodified or N1Ψ modified IL-12 mRNA, with Cap1 structure, optimized codons, engineered UTR and 110nt polyA tail, to improve mRNA stability and translation efficiency.
Product
Interleukin-12 (IL-12) mRNA, Cap1, poly(A) tail, unmodified or modified mRNA
Product Details
| Product |
IL-12 mRNA |
| Cat. No |
mP009 |
| RNA Content |
100 µg~10 mg (OD260) |
| Purity |
A260/A280 |
| Identify and Purity |
Agarose Gel Electrophoresis (AGE) |
| 5’Cap |
Cap1 |
| 3’ poly(A) tail |
110±5 nt |
| Base Modification |
Unmodified, N1Ψ |
| Buffer |
RNase free water (liquid) |
| Shipping |
Ship with dry ice; or under ambient temperature |
| Storage |
● Liquid, at or below -20°C
● Lyophilized powder, at 4°C
|
| Application |
Gene replacement
|
Other Customizable Options
| 5' Cap |
● Uncapped
● Cap0, co-capped
● Cap1, co-capped
● Cap1, enzymatic capping
|
| 5’ UTR/3’ UTR |
● Nature UTR sequence
● Mutant/Engineered UTR sequence
|
| 3' PolyA Tail |
● 100A ~120A Tail (recommended)
● Segmented polyA tail
● Other custom tail
|
| Modified nucleosides |
● Unmodified bases,
● Pseudouridine (Ψ),
● N1-Methylpseudouridine (N1Ψ),
● 5-methylcytosine (m5C),
● 5-methyluridine (m5U),
● 5-methoxyuridine (5moU),
● 2-thiouridine (s2U),
● 2′-O-methyl-U
● Others
|
EN
AR
HR
CS
DA
NL
FI
FR
DE
EL
IT
JA
KO
NO
PL
PT
RO
RU
ES
SV
IW
ID
LV
LT
SR
SK
SL
UK
VI
ET
HU
TH
TR
FA
AF
MS
BE
MK
UR
BN
