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Other Proteins

Other Proteins

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Other Proteins

Microbial expression systems, like bacteria (Escherichia coli) and yeast (Hansenula polymorpha, Pichia pastoris, Saccharomyces cerevisiae) are widely used in the biopharmaceutical industry. Apart from Vaccine, Peptide, Enzyme, Nano-antibody, Antibody fragment, Growth factor, Cytokine, Antigen, and Collagen, the following proteins can also produced in microbial cells.

Types/Family Protein Application
Albumin Human serum albumin (HSA) As an active substance for low albumin levels or as inactive ingredient
Feline serum albumin (FSA) Increasing albumin levels and osmotic pressure
Canine serum albumin (CSA)
Bovine serum albumin (BSA) As a standard reagent in experiments
Chemokine Stromal cell-derived factor-1 (SDF-1) Protecting the heart from ischemia-reperfusion injury; stimulating cardiac angiogenesis
Heparin-binding growth factor Midkine Exerting activities such as angiogenesis and fibrinolysis.
Osteoblast factor MEPE fragment Promoting bone formation and osteoblast proliferation
Apolipoprotein Clusterin (CLU), Apolipoprotein A Clearing cellular debris and apoptosis
E3 ubiquitin ligase Parkin protein Improving Parkinson's symptoms
Annexin Annexin 5 Inhibiting inflammation and endothelial activation as a potential therapeutic for sepsis
Neurotoxic peptides Conopeptides, Conotoxins For pain management, and cosmetics uses (like anti-wrinkle)
Botulinum toxin
Fusion protein Human serum albumin (HSA) fused proteins Improving pharmacokinetic properties and prolonging the half-life of peptides or proteins (mainly as a half-life extension carrier)
Designed ankyrin repeat proteins (DARPins), like DARPins containing HSA-binding domains
Other fusion proteins Custom protein
Yaohai Bio-Pharma Offers One-Stop CDMO Solution for Recombinant Antigen
  • Microbial Strain Engineering and Screening
  • Microbial Cell Banking (PCB/MCB/WCB)
  • Upstream Process Development
  • Downstream Process Development
  • Formulation Development
  • GMP Manufacturing
  • Fill and Finish
  • Analytical and Testing
  • Regulatory Affairs
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