| Cytokine | Members | Source | Characteristics |
| IL, Interleukin | IL-1 | Macrophage, B cells, Dendritic cells (DCs) | Induction of proinflammatory response; Th17 cell differentiation |
| IL-2 | T cells | Proliferation and differentiation into effector and memory T cells; Development of Treg cells, The proliferation of B cells; Proliferation and differentiation of NK cells |
| IL-6 | Th cells, macrophages, fibroblasts | Synthesis of acute-phase proteins in liver, Inducing secretion of chemokines: CCL2, CCL8; CXCL5, CXCL6; Induction of neutrophil apoptosis B cell differentiation and production of IgG, IgM, IgA |
| IL-11 | BM stromal cells | Growth factor for myeloid, erythroid, megakaryocyte progenitors; Bone remodeling; Protects epithelial cells and connective tissue |
| IL-15 | Macrophages, DCs | Induction of Th1 and Th17 responses; Activation of T cell (decreased TCR activation threshold);Survival and proliferation of memory CD8+T cells |
| IL-21 | Th-17 and T follicular helper | Regulation of B cell proliferation, differentiation and apoptosis; Antibody isotype balance (increased IgG and decreased IgE); T cell and NK cell proliferation |
| INF, Interferon | Interferon-α (INF-α) | Leukocytes | Antiviral state; Increases the expression of class I MHC molecules; Activation of NK cells |
| Interferon-β (INF-β) | Fibroblasts | Antiviral state, Increases the expression of class I MHC molecules, Activation of NK cells |
| Interferon-γ (INF-γ) | T-cells | Th1 cell differentiation; Classical activation of macrophages (increased microbicidal functions); Promotes cytotoxic activity; Up-regulation of class I and class II MHC; Increases antigen processing and presentation to T cells; Antiviral properties |
| TNF, Tumor Necrosis factor | TNF-α | Macrophages, Monocytes | Phagocyte cell activation, endotoxic shock; Tumor cytotoxicity, cachexia |
| TNF-β | T-cells | Chemotactic, phagocytosis, oncostatic, induces other cytokines |
| CSF, Colony Stimulating Factor | GM-CSF, CSF-2 | T cells, macrophages, fibroblasts | Granulocyte, monocyte, eosinophil production |
| G-CSF, CSF-3 | Fibroblasts, endothelium | Granulocyte production |
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