Have you ever been sick and needed what your doctor calls medicine so you would feel better? This happens to so many people! Medicine the doctor prescribes is called a drug. Drugs can take many forms, including pills you take by mouth or injections into your arm. These medicines boost your immune system so your body can overcome illness and recover.
There is a whole new method of delivering medicine that is revolutionizing how physicians treat their patients so that patients can be well. The new method is called the circRNA circulation method. An exciting recent approach which helps physicians home in on particular areas of our bodiesℴas well as the genes that cause diseases in other areas of our bodies.
By circling up (circ) in your body, the school helps doctors deliver a drug directly to the cells. This is significant as it enables them to send medicines towards precise genes that can lead to diseases. This will enable them to tackle issues more efficiently. Consider the analogy of having "smart" medicine that is programmed to know exactly where to go to make you feel better. So rather than spwead all over the body this medicine goes directly to the area it is needed.
Where before we send RNA to our cells, a circRNA circulation process is replacing it. It employs circular RNA molecules instead of standard RNA that can degrade quickly. These circular RNAs are stable and able to deliver the drug directly to cells in need. This way, the doctors can target specific cells without upsetting cells that are functioning just as they should.
The traditional methods of delivering medicine can present certain issues. For example, when you swallow a pill or get a shot, the medicine spreads everywhere in your body. That means it can go places that don’t require the medicine at all.” This can lead to side effects for you, and in addition, it can make it more difficult for the medicine to do its thing where it should really be working its hardest.
The circRNA circulation method prevents these issues by allowing doctors to transport the medicine directly to the cells requiring assistance. This is a huge advantage as it means they are able to provide you with a smaller dose of medicine. “With a lower dose, you have fewer opportunities for side effects but still get great results.” It’s a win-win situation!
The unique element is that they possess stability and can last long in the body. They are stable, making them good vehicles for delivering medicine to the cells. Doctors can really harness the power of circRNA by employing it to deliver medicines directly at the genes accountable for the diseases. This targeted technique is called targeted gene therapy and can offer a very exciting way to treat diseases.
circRNA Circulation Method is a Top 10 biotech company specializing in microbiological fermentation. We have built a modern facility with strong RD capabilities and modern manufacturing facilities. Five production lines for pharmaceuticals in line with GMP standards for microbial purification and fermentation along with two automated fill and finish lines for vials and cartridges and pre-filled needles are available. The fermentation scales available are 100L, 500L, 1000L, to 2000L. Specifications for filling vials range from 1ml up to 25ml. the pre-filled syringes and cartridge filling specifications cover between 1-3ml. The workshop for production is cGMP compliant, and guarantees a stable supply of commercial products and clinical samples. Our factory produces large molecules that are shipped around the world.
Yaohai Bio-Pharma is a leading Microbial biologics CDMO. We have been focused on microbial-produced therapeutics and vaccines for human, veterinary, and the management of pet health. We are equipped with circRNA Circulation Method RD platforms as well as manufacturing technology that encompass the entire process beginning with the development of microbial strains cells, methods and processes, to commercial and clinical manufacturing which ensures successful implementation of cutting-edge solutions. We have acquired a large amount of experience in bio processing of microbial cells. We have delivered over 200 global projects, and help our clients with navigating the laws from the US FDA, EU EMA, Australia TGA, and China NMPA. Our professional expertise and extensive experience allows us to quickly respond to market demands and provide tailored CDMO services.
Yaohai BioPharma, a circRNA Circulation Method Microbial CDMO, integrates regulatory affairs and quality management. We have a quality system that is compliant with current GMP standards, as well as regulations around the globe. Our regulatory team is knowledgeable in global regulatory frameworks to expedite biological launches. We make sure that production processes are traceable, high-quality products, and complying with the rules of the US FDA and EU EMA. Australia TGA and China NMPA is also fulfilled. Yaohai BioPharma has successfully passed the audit on site of the European Union's Qualified Person (QP) to ensure our GMP quality system and production site. We also have passed the initial certification audits of the ISO9001 Quality Management System and ISO14001 Environmental Management System.
Yaohai Bio-Pharma is experienced in the development of microbial-derived biologics We offer tailored RD solutions and manufacturing while keeping risks to a minimum We have used a variety of modalities including recombinant subunits vaccines (including peptides) growth factors hormones and Cytokines We've specialized in several microorganisms like yeast intracellular and extracellular secretion (yields up to 15g/L) and bacteria intracellular soluble and inclusion body (yields as high as 10g/L) We have also created a circRNA Circulation Method fermentation system to develop bacteria-based vaccines We are experts in optimizing processes increasing yields as well as reducing production costs Utilizing a strong technology team we ensure timely and quality project delivery to bring your exclusive products to market faster